RESUMO
Objective: The COVID-19 outbreak that has spread all around the world is still a threat for humankind. Epidemiological, clinical, laboratory, and radiological features of the disease are enlightened day by day. It was aimed to evaluate the characteristics of children and their parents with COVID-19 to aid in diagnosis and treatment. Material(s) and Method(s): A retrospective review of the medical records of pediatric patients and their parents who were confirmed as COVID-19 positive, between April 23, and May 28, 2020, was conducted. Result(s): A total of 93 children and 81 adults were evaluated in the present study. Asymptomatic and mild cases accounted for 63.5% of the children and 50% of the parents. Of the children, 3.2% had moderate illness, whereas this was 9.8% for the parents There was a statistically significant difference in terms of the severity of illness between the children and their parents (p =0.01). Although it had a milder clinical course in children, one child died. Increased levels of C-reactive protein (CRP) were observed in 8.6% of the children and 48.1% of the patients, and there was statistically significant difference in terms of CRP levels between the children and their parents (p =0.001). Conclusion(s): The clinical, laboratory, and radiological features of COVID-19 showed differences in the children and their parents. It should be kept in mind that COVID-19 can be fatal in children, although the course of the disease appears to be milder in children than in their parentsCopyright © 2023 Ankara Pediatric Hematology Oncology Training and Research Hospital. All rights reserved.
RESUMO
Objective: Coronavirus disease (COVID-19) is a worldwide pandemic with a huge burden of illness, high economic costs, and mortality rates. This study sought to compare clinical signs and symptoms among adult COVID-19 patients admitted to triage outpatient clinics. Methods: In this observational retrospective study, clinical symptoms, biochemical parameters, and chest computed tomography (CT) of 1745 suspected patients admitted to COVID-19 triage outpatient clinic between 01 April 2020-01 September 2020 were analyzed. Results: A total of 650 (37.2%) of 1745 patients who were admitted to triage outpatient clinic were diagnosed as COVID-19 by PCR confirmation. Of the participants, 88.1% had at least one symptom, 11.9% were asymptomatic. Almost half of the patients (50.1%) had a history of exposure including contact with COVID-19 confirmed cases. COVID-19 (+) patients were more diabetic and hypertensive than negative cases. In patients who underwent chest CT imaging, 40.6% (310) had pneumonic infiltrations compatible with COVID-19 pneumonia. Hemoglobin, leukocyte, neutrophil, lymphocyte, and platelet counts were lower, but CRP levels were higher in patients with COVID-19. Multivariate logistic regression analysis revealed that older age (OR=1.020;p=0.018), contact with confirmed COVID-19 patient (OR=1.907, p=0.009), fever (OR=1,588, p=0,001), fatigue (OR=2.075, p=0.009), cough (OR= 2.301, p<0.001) were significantly associated with increased odds of PCR (+) status. Conclusions: Predictive factors associated with PCR (+) test results were older age, history of contact with confirmed COVID-19 patient, high fever, fatigue, cough in our study. Some symptoms could have a significant relationship with PCR positivity, which requires a more careful approach during the first admission to healthcare facilities.